HEATmarker® is a time-temperature integrator that is applied to temperature-sensitive products to monitor the combined effects of time and temperature.

The complex chemistry of HEATmarker® indicator integrates time and temperature and provides the visual information on the temperature exposure during the supply chain of the product from the manufacturing to the consumer. It monitors a cumulative heat exposure throughout shelf life of the product. They are chosen by the manufacturer based on the stability of the product being monitored.

HEATmarker® VVM has been used to monitor the temperature exposure of vaccines since 1996, (as recommended by the WHO and UNICEF).  Its gradual and permanent irreversible color change  visually shows healthcare workers whether there has been a cumulative heat exposure of the vaccine from the time the VVM is affixed to the vaccine vial by the manufacturer – until the product is used.

HEATmarker VVM+, a key innovation for  the Controlled Temperature Chain (CTC)initiative ,  combines traditional VVM cumulative heat indication with innovative peak temperature indication technology.Temptime developed HEATmarker VVM+ specifically for monitoring heat stable vaccines.  It provides healthcare workers a new level of assurance, in the same historic format as the traditional VVM.  VVM+ visually shows whether there has been either a cumulative heat exposure or a peak heat threshold exposure.